Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837960 | 0.93 | MAPT (0.37) | CD44MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL11840331 | 0.90 | MAPT (0.37) | CD44MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL11830830 | 0.88 | ALDH1A1 (0.32) | MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL27535979 | 0.86 | ALDH1A1 (0.36) | MAPTMEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL11851354 | 0.86 | — | — | |
| SCHEMBL11840457 | 0.86 | KDM4E (0.32) | CD44MAPTMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL11428330 | 0.83 | POLB (0.40) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL11843523 | 0.80 | MEN1 (0.32) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL11833902 | 0.80 | SIGMAR1 (0.30) | — | |
| SCHEMBL11834966 | 0.79 | PDK1 (0.44) | MAPTMEN1ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959488-A | 1-Substituted biguanides for treating hyperacidity or ulceration | WILLIAM H. RORER, INC. (US) | 1976-05-25 | — | — | US | disclosed |