Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11842397 | 0.99 | KDM4E (0.41) | KDM4EHSD17B10TSHRHTR1AADRA2A | |
| SCHEMBL11835521 | 0.86 | HSD17B10 (0.45) | KDM4EHSD17B10TSHRALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11835498 | 0.85 | HSD17B10 (0.44) | KDM4EHSD17B10TSHRALDH1A1MAPT | |
| SCHEMBL11838059 | 0.84 | KDM4E (0.47) | KDM4EHSD17B10TSHRHTR1AADRA2A | |
| SCHEMBL11834839 | 0.79 | POLB (0.43) | KDM4EHSD17B10TSHRALDH1A1MAPT | |
| Oxalic Acid SCHEMBL11834754 | 0.79 | KDM4E (0.51) | KDM4EHSD17B10TSHRALDH1A1MAPT | |
| SCHEMBL11834527 | 0.79 | KDM4E (0.43) | KDM4EHSD17B10TSHRHTR1AHTR7 | |
| SCHEMBL11845306 | 0.79 | KDM4E (0.49) | KDM4EHSD17B10TSHRALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11833169 | 0.78 | PKM (0.42) | KDM4EHSD17B10TSHRALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11843968 | 0.78 | KDM4E (0.42) | KDM4EHSD17B10TSHRHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |