Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18120375 | 0.84 | NQO1 (0.46) | KIF11MAPTFFAR1 | |
| SCHEMBL19532869 | 0.84 | KIF11 (0.36) | KIF11CYP11B1CYP11B2MAOBMAOA | |
| SCHEMBL16473860 | 0.82 | PDK2 (0.41) | KIF11CYP11B1CYP11B2MAOBPOLB | |
| SCHEMBL15496973 | 0.81 | CYP2C9 (0.44) | CYP11B1CYP11B2POLBMAPTSLC7A5 | |
| SCHEMBL21718395 | 0.81 | PDK2 (0.40) | MAOBMAOAMAPT | |
| SCHEMBL21719068 | 0.81 | KIF11 (0.38) | KIF11CYP11B1CYP11B2MAOBPOLB | |
| SCHEMBL1683223 | 0.81 | SMN1; SMN2 (0.45) | KIF11MAOBAOC3SLC7A5 | |
| SCHEMBL21718946 | 0.79 | BRD4 (0.40) | KIF11CYP11B1CYP11B2MAOAFFAR1 | |
| SCHEMBL19240122 | 0.79 | MGLL (0.36) | KIF11CYP11B1CYP11B2POLBMAPT | |
| SCHEMBL21718991 | 0.78 | AGER (0.43) | MAOBMAOAMAPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3981886-A | Amino-benzimidazole derivatives | E. R. SQUIBB & SONS, INC. (US) | 1976-09-21 | — | — | US | disclosed |