Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202861 | 0.89 | PKM (0.44) | PKMKMT2ALMNAMAPTHTT | |
| SCHEMBL3667953 | 0.85 | PKM (0.44) | PKMKMT2ALMNAMAPTHTT | |
| SCHEMBL27930543 | 0.81 | PKM (0.44) | PKMKMT2ALMNAMAPTHTT | |
| SCHEMBL28276642 | 0.80 | MGMT (0.38) | PKMKMT2ALMNAMAPTHTT | |
| SCHEMBL1625081 | 0.80 | LMNA (0.55) | PKMKMT2ALMNAMAPTHTT | |
| SCHEMBL8873122 | 0.80 | PKM (0.41) | PKMKMT2ALMNAMAPTHTT | |
| SCHEMBL10415524 | 0.77 | ALDH1A1 (0.46) | KMT2ALMNAMAPTHTTALDH1A1 | |
| SCHEMBL4927428 | 0.76 | TDP1 (0.50) | PKMKMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL15957606 | 0.76 | TDP1 (0.50) | PKMKMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9465187 | 0.76 | PKM (0.44) | PKMLMNAMAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3943125-A | Substituted tetraamino heterocyclic compounds, useful in the preparation of substituted polybenzimidazoles and poly-imidazopyrrolones | HORIZONS INCORPORATED, A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) | 1976-03-09 | — | — | US | disclosed |