Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824852 | 0.83 | KDM4E (0.36) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11834806 | 0.82 | ALDH1A1 (0.33) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11827166 | 0.77 | MAPT (0.42) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11825844 | 0.76 | SYK (0.31) | — | |
| SCHEMBL11827838 | 0.76 | MAPT (0.39) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11827598 | 0.76 | ESR1 (0.36) | ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL11825801 | 0.75 | TDP1 (0.37) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11825750 | 0.74 | ALDH1A1 (0.34) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11826031 | 0.72 | TDP1 (0.34) | ALDH1A1 | |
| SCHEMBL11825945 | 0.71 | MEN1 (0.37) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |