Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11827598 | 0.88 | ESR1 (0.36) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL11826476 | 0.85 | MAPT (0.35) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL11827838 | 0.85 | MAPT (0.39) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL11823326 | 0.75 | EPHX2 (0.40) | MEN1KMT2AEPHX2TRPV1DHODH | |
| SCHEMBL11834806 | 0.73 | ALDH1A1 (0.33) | KMT2ACYP2D6CYP2C19ALDH1A1MAPT | |
| SCHEMBL11819244 | 0.71 | JUN (0.41) | MEN1KMT2AEPHX2TRPV1DHODH | |
| SCHEMBL11824852 | 0.71 | KDM4E (0.36) | ALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL11834796 | 0.71 | ALDH1A1 (0.34) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11825801 | 0.71 | TDP1 (0.37) | TDP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11827166 | 0.65 | MAPT (0.42) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |