Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158 | 0.88 | MMP9 (0.52) | MMP9MMP8MMP13ADAMTS4FFAR1 | |
| SCHEMBL11831157 | 0.86 | MMP9 (0.55) | MMP9MMP8MMP13ADAMTS4FFAR1 | |
| SCHEMBL11829259 | 0.84 | MMP9 (0.50) | MMP9MMP8MMP13ADAMTS4FFAR1 | |
| SCHEMBL7345068 | 0.75 | FFAR1 (0.52) | MMP9MMP8MMP13ADAMTS4FFAR1 | |
| SCHEMBL11838193 | 0.73 | FFAR1 (0.50) | MMP9MMP8MMP13ADAMTS4FFAR1 | |
| SCHEMBL28710491 | 0.73 | MMP9 (0.51) | MMP9MMP8MMP13ADAMTS4FFAR1 | |
| SCHEMBL877721 | 0.73 | FFAR1 (0.50) | MMP9MMP8MMP13ADAMTS4FFAR1 | |
| SCHEMBL11828935 | 0.73 | FFAR1 (0.50) | MMP9MMP8MMP13ADAMTS4FFAR1 | |
| SCHEMBL11822261 | 0.73 | FFAR1 (0.50) | MMP9MMP8MMP13ADAMTS4FFAR1 | |
| SCHEMBL11823952 | 0.73 | CHRNB2 (0.50) | MMP9MMP8MMP13ADAMTS4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |