Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 7/20 | 0.49 |
| ▸ | MMP13 | P45452 | 6/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | CPA3 | P15088 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829707 | 0.84 | ABCC4 (0.39) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL11834123 | 0.83 | PPARG (0.53) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL11826199 | 0.83 | CSNK2A1 (0.53) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL11830862 | 0.82 | ALDH1A1 (0.39) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL11837906 | 0.79 | ALDH1A1 (0.45) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL6800633 | 0.78 | MMP12 (0.70) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL379630 | 0.78 | MMP12 (0.70) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL11835452 | 0.78 | CD274 (0.43) | TRPA1PDCD1CD274FOLH1PPARG | |
| SCHEMBL11830281 | 0.78 | CD274 (0.43) | PDCD1CD274FOLH1PPARGPPARA | |
| SCHEMBL11830311 | 0.74 | MMP12 (0.42) | MMP12MMP13MMP2MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |