Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830736 | 0.85 | ALDH1A1 (0.43) | PPARGPPARAKMT2AMMEACE | |
| SCHEMBL11835452 | 0.84 | CD274 (0.43) | CD274PDCD1PPARGPPARAPTGS1 | |
| SCHEMBL11834506 | 0.84 | CSNK2A1 (0.50) | CD274PPARGPPARA | |
| SCHEMBL11823672 | 0.80 | PDCD1 (0.43) | CD274PDCD1KMT2AMEN1PTGS2 | |
| SCHEMBL11835446 | 0.78 | MMP12 (0.49) | CD274PDCD1PPARGPPARAFOLH1 | |
| SCHEMBL11830311 | 0.75 | MMP12 (0.42) | CD274PDCD1KMT2AMMEACE | |
| SCHEMBL11830862 | 0.74 | ALDH1A1 (0.39) | CD274PDCD1PPARGPPARAFOLH1 | |
| SCHEMBL11829707 | 0.74 | ABCC4 (0.39) | CD274PDCD1PTGS1TSHRLMNA | |
| SCHEMBL11830972 | 0.74 | MME (0.50) | PPARGPPARAKMT2AMEN1CYP2C19 | |
| SCHEMBL11838658 | 0.74 | MME (0.47) | PPARGPPARAKMT2AMEN1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |