Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | TLR4 | O00206 | 1/20 | 0.54 |
| ▸ | TLR2 | O60603 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223073 | 0.87 | MEN1 (0.75) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL8306021 | 0.85 | RAB9A (0.63) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL11823640 | 0.85 | ALDH1A1 (0.54) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL20558332 | 0.84 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL11829327 | 0.83 | ALDH1A1 (0.56) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL11828243 | 0.83 | MEN1 (0.64) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL11836074 | 0.82 | ALDH1A1 (0.54) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2749120 | 0.82 | ALDH1A1 (0.69) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL11830698 | 0.82 | SORT1 (0.55) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL11837121 | 0.81 | ALDH1A1 (0.62) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3995044-A | Pyridine carboxylic acid amides for mycobacterium infections | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-30 | — | — | US | disclosed |