Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835649 | 1.00 | GAA (0.60) | GAAGFERCYP19A1MAPTLMNA | |
| SCHEMBL11830899 | 0.84 | MAPT (0.56) | GAAGFERCYP19A1MAPTLMNA | |
| SCHEMBL6706751 | 0.81 | CYP19A1 (0.65) | GAAGFERCYP19A1MAPTLMNA | |
| SCHEMBL11838800 | 0.78 | GAA (0.38) | GAAGFERCYP19A1MAPTLMNA | |
| SCHEMBL11838806 | 0.78 | GAA (0.38) | GAAGFERCYP19A1MAPTLMNA | |
| SCHEMBL11437742 | 0.77 | CTBP2 (0.56) | — | |
| SCHEMBL11837951 | 0.75 | HTR6 (0.60) | CNR2 | |
| SCHEMBL11837942 | 0.75 | HTR6 (0.60) | CNR2 | |
| SCHEMBL4364200 | 0.75 | RAB9A (0.71) | GAAGFERMAPTLMNAMEN1 | |
| SCHEMBL9502361 | 0.74 | CYP19A1 (0.57) | GAAGFERCYP19A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933853-A | ANALGESICS, TRANQUILIZERS | CLIN MIDY (FR) | 1976-01-20 | — | — | US | disclosed |