Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HK2 | P52789 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11844073 | 0.85 | HK2 (0.41) | CYP3A4USP2MAPK1SMN1; SMN2HTT | |
| SCHEMBL11779271 | 0.71 | HTT (0.51) | CYP3A4USP2MAPK1SMN1; SMN2HTT | |
| SCHEMBL11848652 | 0.70 | ALDH1A1 (0.41) | CYP3A4USP2MAPK1SMN1; SMN2CNR2 | |
| SCHEMBL11838892 | 0.69 | KDM4E (0.38) | USP2ABCG2LMNACA1CA2 | |
| SCHEMBL11846669 | 0.68 | MAPT (0.38) | CYP3A4MAPK1SMN1; SMN2HTTCNR2 | |
| SCHEMBL21784054 | 0.68 | PTGES (0.49) | CYP3A4USP2MAPK1SMN1; SMN2CA1 | |
| SCHEMBL27981979 | 0.67 | PDE4D (0.47) | CYP3A4USP2MAPK1SMN1; SMN2HTT | |
| SCHEMBL11845954 | 0.64 | ESR1 (0.38) | USP2LMNACA1CA2CA9 | |
| SCHEMBL11838374 | 0.64 | ALDH1A1 (0.43) | SMN1; SMN2LMNACA1CA2CA9 | |
| SCHEMBL9752687 | 0.63 | CYP3A4 (0.65) | CYP3A4USP2MAPK1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987186-A | ANTIALLERGENS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-10-19 | — | — | US | disclosed |