Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 14/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11832989 | 0.86 | S1PR1 (0.47) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL11828721 | 0.86 | S1PR1 (0.47) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL11834848 | 0.82 | THRB (0.41) | S1PR1S1PR3 | |
| SCHEMBL11835864 | 0.82 | PTGDR2 (0.40) | S1PR1S1PR3 | |
| SCHEMBL11837327 | 0.80 | S1PR1 (0.43) | S1PR1 | |
| SCHEMBL3846473 | 0.78 | S1PR1 (0.44) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL27876622 | 0.78 | S1PR1 (0.44) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL30418848 | 0.78 | S1PR1 (0.44) | S1PR1S1PR3S1PR4S1PR5ADORA3 | |
| SCHEMBL11844523 | 0.78 | SLC9A1 (0.36) | — | |
| SCHEMBL11833519 | 0.78 | SLC18A3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985788-A | Phenyl propionic acids and derivatives thereof | WILLIAM H. RORER, INC. (US) | 1976-10-12 | — | — | US | disclosed |