Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836837 | 0.78 | HPN (0.43) | HPNSCN2AMEN1KMT2AGAA | |
| SCHEMBL11842845 | 0.77 | MGLL (0.51) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL11836629 | 0.75 | SCN2A (0.68) | HPNSCN2AMEN1KMT2AMAPT | |
| SCHEMBL10854270 | 0.75 | HPN (0.68) | HPNSCN2AMEN1KMT2AGAA | |
| SCHEMBL3190723 | 0.75 | HPN (0.55) | HPNSCN2AMEN1KMT2AGAA | |
| SCHEMBL3190732 | 0.75 | HPN (0.55) | HPNSCN2AMEN1KMT2AGAA | |
| SCHEMBL3190715 | 0.75 | HPN (0.55) | HPNSCN2AMEN1KMT2AGAA | |
| SCHEMBL11836918 | 0.74 | MEN1 (0.53) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL3868871 | 0.74 | HPN (0.60) | HPNSCN2AMEN1KMT2AGAA | |
| SCHEMBL2029909 | 0.73 | HPN (1.00) | HPNSCN2AMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966931-A | TRANQUILIZERS, ANTICONVULSANTS, HYPNOSIS | RHONE-POULENC S.A. (FR) | 1976-06-29 | — | — | US | disclosed |
| US-3948917-A | TRANQUILIZERS, ANTICONVULSANTS, DECONTRACTURANTS, HYPNOSIS | RHONE-POULENC S.A. (FR) | 1976-04-06 | — | — | US | disclosed |