Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.57 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNG | P07510 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262552 | 0.82 | NR4A2 (0.69) | NR4A2CREBBPKMT2AALDH1A1PBRM1 | |
| SCHEMBL730525 | 0.76 | NR4A2 (0.69) | NR4A2CREBBPKMT2AALDH1A1PBRM1 | |
| Hydrochloric Acid SCHEMBL30718988 | 0.75 | NR4A2 (0.67) | NR4A2CREBBPKMT2AALDH1A1PBRM1 | |
| Hydrochloric Acid SCHEMBL28308377 | 0.75 | NR4A2 (0.67) | NR4A2CREBBPKMT2AALDH1A1PBRM1 | |
| SCHEMBL11816233 | 0.74 | CCR1 (0.45) | KMT2AALDH1A1LMNAMEN1CYP3A4 | |
| SCHEMBL11827213 | 0.74 | CCR1 (0.45) | LMNA | |
| SCHEMBL30031033 | 0.74 | NR4A2 (1.00) | NR4A2CREBBPKMT2AALDH1A1PBRM1 | |
| SCHEMBL1093530 | 0.74 | NR4A2 (1.00) | NR4A2CREBBPKMT2AALDH1A1PBRM1 | |
| SCHEMBL5162767 | 0.73 | KMT2A (0.69) | NR4A2CREBBPKMT2AALDH1A1PBRM1 | |
| SCHEMBL7615992 | 0.73 | CYP2D6 (0.58) | NR4A2CREBBPKMT2AALDH1A1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29003-E | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3956323-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-11 | — | — | US | disclosed |