Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.69 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.69 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.54 |
| ▸ | CHRNG | P07510 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464228 | 0.84 | PBRM1 (0.61) | NR4A2CREBBPPBRM1ALDH1A1KMT2A | |
| SCHEMBL11836645 | 0.82 | NR4A2 (0.57) | NR4A2CREBBPPBRM1ALDH1A1KDM4E | |
| SCHEMBL1093530 | 0.81 | NR4A2 (1.00) | NR4A2CREBBPPBRM1ALDH1A1KMT2A | |
| SCHEMBL30031033 | 0.81 | NR4A2 (1.00) | NR4A2CREBBPPBRM1ALDH1A1KMT2A | |
| SCHEMBL21438344 | 0.81 | AHR (0.59) | NR4A2CREBBPPBRM1ALDH1A1KDM4E | |
| SCHEMBL7096698 | 0.81 | LMNA (0.57) | NR4A2CREBBPPBRM1ALDH1A1HPGD | |
| SCHEMBL27683686 | 0.81 | PBRM1 (0.56) | NR4A2CREBBPPBRM1ALDH1A1KDM4E | |
| SCHEMBL7615992 | 0.81 | CYP2D6 (0.58) | NR4A2CREBBPPBRM1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL28254334 | 0.80 | NR4A2 (0.97) | NR4A2CREBBPPBRM1ALDH1A1KMT2A | |
| SCHEMBL7496719 | 0.79 | KDM4E (0.54) | NR4A2CREBBPPBRM1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008727-A1 | ASYMMETRIC SYNTHESIS OF ALLYL OR ALLENE OXINDOLES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-01-21 | — | — | WO | disclosed |
| US-5880126-A | 9H-Pyridu ((3,4-b) indole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |