SCHEMBL2393760

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9890768	0.88	PDE4B (0.45)	CHRM1CHRM3CYP2C19PDE4BCYP3A4
	SCHEMBL2391279	0.87	CYP2C19 (0.48)	CHRM1CHRM3CYP2C19SLC9A1ACLY
	SCHEMBL9890642	0.86	CHRM1 (0.57)	CHRM1CHRM3PTGER1PTGER4PTGER3
	SCHEMBL6098745	0.84	PTGER4 (0.62)	PTGER1PTGER4PTGER3PTGER2ACLY
	SCHEMBL9890733	0.82	ICMT (0.44)	CHRM1CHRM3CYP2C19PDE4BCYP3A4
	SCHEMBL2395113	0.82	CHRM1 (0.45)	CHRM1CHRM3CYP2C19PDE4BCYP3A4
	SCHEMBL6184923	0.82	CYP2C19 (0.64)	CYP2C19ACLY
	SCHEMBL9295512	0.81	CHRM1 (0.54)	CHRM1CHRM3CYP2C19PTGER1PTGER4
	SCHEMBL1547038	0.81	KMT2A (0.56)	CYP2C19PTGER1PTGER4PTGER3PTGER2
	SCHEMBL2392257	0.81	ICMT (0.54)	PTGER1PTGER4PTGER3PTGER2SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.