Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826532 | 0.86 | CSNK2A1 (0.46) | MMEHCAR2FFAR1 | |
| SCHEMBL11834777 | 0.85 | MMP12 (0.48) | MMEMMEL1FFAR1 | |
| SCHEMBL6155924 | 0.82 | CPA1 (0.51) | MEN1KMT2A | |
| SCHEMBL11837145 | 0.82 | DPP4 (0.40) | MMEFFAR2MEN1KMT2A | |
| SCHEMBL11824499 | 0.79 | MME (0.62) | MMEMAOBMMEL1HCAR2CYP2A6 | |
| SCHEMBL11828626 | 0.79 | MME (0.62) | MMEMAOBMMEL1HCAR2ITGB1 | |
| SCHEMBL11822857 | 0.77 | PTGS1 (0.47) | MEN1KMT2A | |
| SCHEMBL11831427 | 0.75 | MAOB (0.47) | MMEMAOBHCAR2ITGB1ITGA4 | |
| SCHEMBL11828266 | 0.75 | MMP12 (0.46) | MMEMMEL1FFAR1 | |
| SCHEMBL11832270 | 0.75 | SRR (0.46) | MMEFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |