Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 5/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837137 | 0.82 | MME (0.55) | MMEKMT2AFFAR2MEN1 | |
| SCHEMBL11828631 | 0.77 | DPP4 (0.46) | DPP4MMEKMT2AFFAR2CTSA | |
| SCHEMBL6155924 | 0.75 | CPA1 (0.51) | KMT2ATSHRMEN1HPGD | |
| SCHEMBL11831432 | 0.74 | DPP4 (0.40) | DPP4HSP90AA1HSP90AB1KMT2ATSHR | |
| SCHEMBL11826532 | 0.73 | CSNK2A1 (0.46) | MME | |
| SCHEMBL11834777 | 0.71 | MMP12 (0.48) | MMETSHR | |
| SCHEMBL9890641 | 0.70 | CXCL8 (0.57) | DPP4CXCL8 | |
| SCHEMBL7037470 | 0.70 | MMP12 (0.47) | DPP4KMT2ATSHRMEN1HPGD | |
| SCHEMBL11831274 | 0.69 | GABRA1 (0.39) | AKR1C2 | |
| SCHEMBL11824498 | 0.68 | CDC25A (0.37) | MMEHSP90AA1HSP90AB1CTSAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |