Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11790207 | 0.84 | CASP1 (0.47) | GRM6ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL11836185 | 0.84 | GRM6 (0.42) | GRM6ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL11842029 | 0.83 | GRM6 (0.41) | GRM6ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL11838428 | 0.83 | GRM6 (0.41) | GRM6ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL11839287 | 0.79 | CYP2A6 (0.52) | ALDH1A1NPSR1CYP2A6MAOBAKR1C3 | |
| SCHEMBL11841294 | 0.79 | KDM4E (0.39) | GRM6ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL11827342 | 0.79 | AKR1C3 (0.40) | GRM6ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL11839776 | 0.79 | PGR (0.40) | GRM6ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL11828131 | 0.79 | MAOB (0.50) | GRM6ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL11834108 | 0.79 | ALDH1A1 (0.40) | GRM6ALDH1A1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |