Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.75 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.66 |
| ▸ | TNKS | O95271 | 1/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.66 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamic Acid SCHEMBL11837266 | 1.00 | MAPT (0.75) | MAPTHCAR2HDAC3HDAC4HDAC1 | |
| Coumaric Acid SCHEMBL21571613 | 0.91 | ESR1 (0.64) | MAPTHCAR2HDAC3HDAC4HDAC1 | |
| Anthranilic Acid SCHEMBL23357449 | 0.87 | MAPT (0.59) | MAPTHCAR2HDAC3HDAC4HDAC1 | |
| SCHEMBL1501351 | 0.86 | MAPT (1.00) | MAPTHCAR2HDAC3HDAC4HDAC1 | |
| SCHEMBL1501349 | 0.86 | MAPT (1.00) | MAPTHCAR2HDAC3HDAC4HDAC1 | |
| Anthranilic Acid SCHEMBL31255846 | 0.81 | MAPT (0.60) | MAPTHDAC8RECQLSMN1; SMN2ALDH1A1 | |
| Anthranilic Acid SCHEMBL3110791 | 0.81 | ALDH1A1 (0.65) | MAPTHDAC8RECQLSMN1; SMN2ALDH1A1 | |
| Cinnamic Acid SCHEMBL50466 | 0.81 | HCAR2 (1.00) | MAPTHCAR2HDAC3HDAC4HDAC1 | |
| Cinnamic Acid SCHEMBL1332 | 0.81 | HCAR2 (1.00) | MAPTHCAR2HDAC3HDAC4HDAC1 | |
| Cinnamic Acid SCHEMBL653828 | 0.81 | HCAR2 (1.00) | MAPTHCAR2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998974-A | Comestibles containing non-nutritive flavoring | DYNAPOL CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |