Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11840747 | 1.00 | HCAR2 (0.36) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| SCHEMBL11835568 | 0.82 | PPARA (0.38) | ALDH1A1 | |
| SCHEMBL11835563 | 0.82 | PPARA (0.38) | ALDH1A1 | |
| SCHEMBL7544647 | 0.81 | ALDH1A1 (0.39) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| SCHEMBL7544646 | 0.81 | ALDH1A1 (0.39) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| SCHEMBL11846847 | 0.80 | ZDHHC20 (0.35) | — | |
| SCHEMBL11846853 | 0.80 | ZDHHC20 (0.35) | — | |
| SCHEMBL11763568 | 0.79 | ALDH1A1 (0.51) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| SCHEMBL11763572 | 0.79 | ALDH1A1 (0.51) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| SCHEMBL11842673 | 0.79 | ALOX15 (0.45) | HCAR2KEAP1NFE2L2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966780-A | PESTICIDES, INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1976-06-29 | — | — | US | disclosed |