Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 3/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11843963 | 0.93 | ALOX15 (0.48) | ALOX15AURKBMAPTAURKASMN1; SMN2 | |
| SCHEMBL11843783 | 0.91 | ALOX15 (0.46) | ALOX15MAPTSMN1; SMN2SENP1CISD1 | |
| SCHEMBL11849129 | 0.90 | MAPT (0.46) | ALOX15AURKBMAPTAURKASMN1; SMN2 | |
| SCHEMBL11853481 | 0.90 | MAPT (0.49) | ALOX15MAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL11855966 | 0.89 | CISD1 (0.47) | MAPTL3MBTL1NPC1RECQLRAB9A | |
| SCHEMBL11840275 | 0.89 | RXFP1 (0.47) | ALOX15MAPTTP53NPSR1RXFP1 | |
| SCHEMBL11846270 | 0.88 | ALOX15 (0.44) | ALOX15MAPTSMN1; SMN2SENP1CDC25B | |
| SCHEMBL11854968 | 0.87 | CISD1 (0.45) | ALOX15MAPTSMN1; SMN2CISD1TP53 | |
| SCHEMBL11852452 | 0.87 | ALOX15 (0.46) | ALOX15MAPTSMN1; SMN2CISD1TP53 | |
| SCHEMBL11843685 | 0.86 | MAPT (0.44) | ALOX15MAPTL3MBTL1SMN1; SMN2CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |