Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25C | P30307 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11843685 | 0.91 | MAPT (0.44) | MAPTTP53ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11843963 | 0.91 | ALOX15 (0.48) | MAPTSMN1; SMN2ALOX15CA2MEN1 | |
| SCHEMBL11838101 | 0.90 | ALOX15 (0.44) | MAPTTP53CDC25BALDH1A1SMN1; SMN2 | |
| SCHEMBL11846270 | 0.88 | ALOX15 (0.44) | MAPTCDC25BCDC25ACDC25CSMN1; SMN2 | |
| SCHEMBL11853481 | 0.87 | MAPT (0.49) | MAPTALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL11840275 | 0.87 | RXFP1 (0.47) | MAPTTP53EGFRLMNAALOX15 | |
| SCHEMBL11843783 | 0.86 | ALOX15 (0.46) | MAPTTP53ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11854968 | 0.85 | CISD1 (0.45) | MAPTTP53ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11852452 | 0.81 | ALOX15 (0.46) | MAPTTP53ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11845448 | 0.81 | ALOX15 (0.47) | MAPTALDH1A1SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |