Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11853481 | 0.93 | MAPT (0.49) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL11843963 | 0.93 | ALOX15 (0.48) | MAPTSMN1; SMN2MEN1KMT2AALOX15 | |
| SCHEMBL11843783 | 0.92 | ALOX15 (0.46) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL11849129 | 0.91 | MAPT (0.46) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL11854968 | 0.90 | CISD1 (0.45) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL11850459 | 0.90 | PPARA (0.46) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL11846270 | 0.89 | ALOX15 (0.44) | MAPTSMN1; SMN2MEN1KMT2AALOX15 | |
| SCHEMBL11838101 | 0.86 | ALOX15 (0.44) | MAPTSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL11840282 | 0.85 | ALDH1A1 (0.55) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL11840275 | 0.83 | RXFP1 (0.47) | MAPTLMNAALOX15SLC2A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |