Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7159469 | 0.98 | KDM4E (0.57) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL11810182 | 0.82 | LMNA (0.58) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL9168592 | 0.82 | TSHR (0.43) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL9168598 | 0.82 | TSHR (0.43) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL9168593 | 0.82 | TSHR (0.43) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL7158370 | 0.81 | TSHR (0.61) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL9034838 | 0.80 | TSHR (0.39) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL10508084 | 0.79 | TSHR (0.45) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL9032390 | 0.79 | TSHR (0.43) | KDM4ELMNAGAAPOLBALDH1A1 | |
| SCHEMBL5815739 | 0.78 | TSHR (0.61) | KDM4EGAAALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956341-A | 1,3,5-Tricarbo-1,4-dihydropyridines | SMITHKLINE CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |