Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2883308 | 0.89 | HCAR3 (0.55) | MAPTKMT2AMEN1TDP1HCAR3 | |
| SCHEMBL11843965 | 0.88 | MAPT (0.51) | MAPTFBP1KMT2AMEN1MAPK1 | |
| SCHEMBL11847173 | 0.86 | MAPT (0.62) | MAPTFBP1KMT2AMEN1HPGD | |
| SCHEMBL11849835 | 0.84 | AKR1C3 (0.54) | MAPTFBP1KMT2AMEN1MAPK1 | |
| SCHEMBL11849602 | 0.84 | MAPT (0.51) | MAPTKMT2AMEN1TDP1HCAR3 | |
| SCHEMBL11842798 | 0.83 | NPSR1 (0.44) | MAPTKMT2AMEN1TDP1MAPK1 | |
| SCHEMBL11840971 | 0.83 | MAPT (0.47) | MAPTKMT2AMEN1TDP1MAPK1 | |
| SCHEMBL11848500 | 0.83 | KMT2A (0.50) | MAPTKMT2AMEN1TDP1HTT | |
| SCHEMBL11836594 | 0.82 | KMT2A (0.46) | MAPTKMT2AMEN1TDP1MAPK1 | |
| SCHEMBL11783509 | 0.81 | MAPT (0.60) | MAPTKMT2AMEN1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |