Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | FBP1 | P09467 | 4/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11840178 | 0.89 | MAPT (0.60) | MAPTHPGDAKR1B10AKR1B1AKR1C4 | |
| SCHEMBL11839665 | 0.86 | MAPT (0.52) | MAPTHPGDAKR1B10AKR1B1AKR1C4 | |
| SCHEMBL2883308 | 0.86 | HCAR3 (0.55) | MAPTAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11845912 | 0.84 | NPC1 (0.61) | MAPTHPGDAKR1C3AKR1C2CA2 | |
| SCHEMBL11842723 | 0.82 | MAPT (0.63) | MAPTHPGDFBP1GAAMEN1 | |
| SCHEMBL11848500 | 0.82 | KMT2A (0.50) | MAPTHPGDAKR1C3CA2MEN1 | |
| SCHEMBL21436556 | 0.82 | VCAM1 (0.50) | MAPTAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11849835 | 0.82 | AKR1C3 (0.54) | MAPTAKR1B1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL11849602 | 0.81 | MAPT (0.51) | MAPTAKR1C3AKR1C2GAAMEN1 | |
| SCHEMBL11843965 | 0.81 | MAPT (0.51) | MAPTAKR1C3AKR1C2FBP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |