Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836594 | 0.93 | KMT2A (0.46) | MAPTKDM4EALDH1A1HCAR3TDP1 | |
| SCHEMBL2883308 | 0.93 | HCAR3 (0.55) | MAPTKDM4EALDH1A1HCAR3TDP1 | |
| SCHEMBL11849870 | 0.92 | KMT2A (0.45) | MAPTKDM4EALDH1A1HCAR3KMT2A | |
| SCHEMBL11843965 | 0.92 | MAPT (0.51) | MAPTKDM4EALDH1A1HCAR3KMT2A | |
| SCHEMBL11783509 | 0.90 | MAPT (0.60) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL11840178 | 0.89 | MAPT (0.60) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL11848500 | 0.86 | KMT2A (0.50) | MAPTKDM4EALDH1A1HCAR3TDP1 | |
| SCHEMBL11839665 | 0.84 | MAPT (0.52) | MAPTHCAR3TDP1KMT2AMEN1 | |
| SCHEMBL11849835 | 0.81 | AKR1C3 (0.54) | MAPTKDM4EHCAR3KMT2AMEN1 | |
| SCHEMBL11847173 | 0.81 | MAPT (0.62) | MAPTKMT2AMEN1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |