Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.30 |
| ▸ | FDPS | P14324 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11839821 | 1.00 | ALOX15 (0.43) | ALOX15ALDH1A1USP2ZDHHC20NFE2L2 | |
| SCHEMBL11756161 | 0.84 | ALDH1A1 (0.42) | ALOX15ALDH1A1USP2ZDHHC20TSHR | |
| SCHEMBL11756165 | 0.84 | ALDH1A1 (0.42) | ALOX15ALDH1A1USP2ZDHHC20TSHR | |
| SCHEMBL11846853 | 0.82 | ZDHHC20 (0.35) | ZDHHC20 | |
| SCHEMBL11845229 | 0.82 | ZDHHC20 (0.38) | ALDH1A1ZDHHC20TSHR | |
| SCHEMBL11845237 | 0.82 | ZDHHC20 (0.38) | ALDH1A1ZDHHC20TSHR | |
| SCHEMBL11846847 | 0.82 | ZDHHC20 (0.35) | ZDHHC20 | |
| SCHEMBL11842673 | 0.81 | ALOX15 (0.45) | ALOX15ALDH1A1USP2NFE2L2TSHR | |
| SCHEMBL11849438 | 0.81 | ALOX15 (0.45) | ALOX15ALDH1A1USP2NFE2L2TSHR | |
| SCHEMBL11840117 | 0.80 | CYP3A4 (0.38) | ALDH1A1ZDHHC20TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966780-A | PESTICIDES, INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1976-06-29 | — | — | US | claimed |
| US-3966780-A | PESTICIDES, INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1976-06-29 | — | — | US | disclosed |