Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11843722 | 0.82 | HTR2B (0.38) | HTR2CHTR6HTR2BHTR7TMEM97 | |
| SCHEMBL7140355 | 0.80 | HTR2C (0.42) | HTR2CHTR6SRD5A1HTR2BHTR2A | |
| SCHEMBL15999467 | 0.80 | HTR2C (0.42) | HTR2CHTR6SRD5A1HTR2BHTR2A | |
| SCHEMBL20370870 | 0.80 | SRD5A1 (0.46) | HTR6SRD5A1ALDH1A1KDM4EMAPT | |
| SCHEMBL5020544 | 0.80 | ALDH1A1 (0.46) | HTR6SRD5A1ALDH1A1KDM4EMAPT | |
| SCHEMBL20370873 | 0.78 | SRD5A1 (0.44) | HTR6SRD5A1ALDH1A1KDM4EMAPT | |
| SCHEMBL20370875 | 0.78 | SRD5A1 (0.44) | HTR6SRD5A1ALDH1A1KDM4EMAPT | |
| SCHEMBL8032476 | 0.78 | ALDH1A1 (0.42) | HTR6ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL12132122 | 0.76 | APP (0.48) | HTR2CMEN1KMT2A | |
| SCHEMBL6215962 | 0.75 | HTR2C (0.43) | HTR2CSRD5A1HTR2BHTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3983239-A | PSYCHOTROPIC | DAINIPPON PHARMACEUTICAL CO., LTD. (JA) | 1976-09-28 | — | — | US | disclosed |