Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11849184 | 0.84 | NQO2 (0.39) | ALDH1A1KDM4EMEN1MAPTTSHR | |
| SCHEMBL11842696 | 0.82 | GPR35 (0.42) | GPR35HCAR2HCAR3ALDH1A1KDM4E | |
| SCHEMBL11844465 | 0.82 | GPR35 (0.47) | GPR35HCAR2HCAR3ALDH1A1KDM4E | |
| SCHEMBL11844604 | 0.76 | NR4A2 (0.38) | ALDH1A1KDM4EMEN1LMNAMAPT | |
| SCHEMBL11841924 | 0.76 | NPC1 (0.38) | KDM4EMEN1CYP3A4PKMKMT2A | |
| SCHEMBL16701192 | 0.74 | HCAR2 (0.47) | GPR35HCAR2HCAR3ALDH1A1KDM4E | |
| SCHEMBL11856246 | 0.74 | MAPT (0.36) | ALDH1A1KDM4ELMNACYP1A2MAPT | |
| SCHEMBL11838424 | 0.73 | LMNA (0.42) | HCAR2HCAR3LMNACYP1A2L3MBTL1 | |
| SCHEMBL11838534 | 0.73 | LMNA (0.42) | HCAR2HCAR3LMNACTRCGABRP | |
| SCHEMBL5671324 | 0.71 | AKR1C2 (0.49) | ALDH1A1KDM4ECYP3A4TSHRCTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998955-A | 2-CARBOXY OR 2-ALKOXYCARBONYL-PYRIDINES | CIBA-GEIGY CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |