Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13237026 | 0.82 | ALDH1A1 (0.38) | MAPK1HPGDHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL11841924 | 0.80 | NPC1 (0.38) | MAPK1RAB9ANPC1HPGDHTT | |
| SCHEMBL11840604 | 0.76 | GPR35 (0.46) | MAPK1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15819989 | 0.76 | POLB (0.44) | NR4A2MAPK1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL29880065 | 0.76 | ALDH1A1 (0.41) | MAPK1HPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1710375 | 0.76 | ALDH1A1 (0.41) | MAPK1HPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL649387 | 0.73 | HPGD (0.37) | NR4A2MAPK1RAB9ANPC1HPGD | |
| SCHEMBL11849184 | 0.73 | NQO2 (0.39) | MAPK1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8106157 | 0.73 | NPC1 (0.43) | MAPK1RAB9ANPC1HPGDHTT | |
| SCHEMBL12495762 | 0.73 | PDK2 (0.42) | MAPK1RAB9ANPC1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998955-A | 2-CARBOXY OR 2-ALKOXYCARBONYL-PYRIDINES | CIBA-GEIGY CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |