Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748374 | 0.96 | KDM4E (0.50) | KDM4EHPGDHTTALDH1A1TSHR | |
| SCHEMBL16548465 | 0.90 | KDM4E (0.53) | KDM4EHPGDHTTALDH1A1TSHR | |
| SCHEMBL22534570 | 0.87 | HSD17B3 (0.54) | KDM4EHPGDHTTALDH1A1TSHR | |
| SCHEMBL11812982 | 0.85 | KDM4E (0.48) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL4889003 | 0.83 | HPD (0.49) | KDM4EALDH1A1MAPT | |
| SCHEMBL11810127 | 0.83 | KDM4E (0.55) | KDM4EHPGDHTTALDH1A1TSHR | |
| SCHEMBL12319300 | 0.82 | ALDH1A1 (0.46) | KDM4EHPGDHTTALDH1A1LMNA | |
| SCHEMBL11812736 | 0.82 | SIGMAR1 (0.51) | KDM4EHPGDHTTALDH1A1TSHR | |
| SCHEMBL16281543 | 0.81 | CNR2 (0.41) | KDM4EHPGDHTTALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL11834867 | 0.81 | SIGMAR1 (0.50) | KDM4EHPGDHTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962451-A | ANTIVIRAL | RICHARDSON-MERRELL INC. (US) | 1976-06-08 | — | — | US | disclosed |