Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MYOC | Q99972 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842419 | 0.85 | NTRK1 (0.52) | HSPB1GSK3AGSK3BATMLTA4H | |
| SCHEMBL9187712 | 0.78 | GSK3A (0.56) | GSK3AGSK3BKMT2AMEN1MAPT | |
| SCHEMBL2011179 | 0.76 | HSPB1 (0.79) | HSPB1LTA4HPTGS1PTGS2KMT2A | |
| SCHEMBL11689190 | 0.76 | HSPB1 (0.79) | HSPB1LTA4HPTGS1PTGS2KMT2A | |
| SCHEMBL9183872 | 0.76 | HSPB1 (0.79) | HSPB1LTA4HPTGS1PTGS2KMT2A | |
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL134332 | 0.76 | HSPB1 (0.79) | HSPB1LTA4HPTGS1PTGS2KMT2A | |
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL8934595 | 0.74 | HSPB1 (0.76) | HSPB1LTA4HPTGS1PTGS2KMT2A | |
| SCHEMBL20238568 | 0.71 | HSPB1 (0.56) | HSPB1LTA4HPTGS1PTGS2KMT2A | |
| SCHEMBL177626 | 0.71 | HSPB1 (0.66) | HSPB1PTGS1PTGS2KMT2AMEN1 | |
| SCHEMBL8695353 | 0.71 | HSD17B10 (0.75) | HSPB1KMT2AMEN1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933814-A | ANTIPROTOZOA, ANTICOCCIDIOSIS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |