Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | AR | P10275 | 5/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13009600 | 0.85 | MAPT (0.53) | MAPTLMNAKDM4ERAB9AGAA | |
| SCHEMBL11842785 | 0.84 | MAPT (0.52) | MAPTLMNAKDM4ERAB9AGAA | |
| SCHEMBL11847293 | 0.82 | MEN1 (0.43) | MAPTLMNAKDM4EGAAL3MBTL1 | |
| SCHEMBL11838414 | 0.80 | MAPT (0.51) | MAPTLMNARAB9AGAAPRKCZ | |
| SCHEMBL10771702 | 0.80 | MAPT (0.57) | MAPTLMNAKDM4EGAAAR | |
| SCHEMBL11850461 | 0.80 | PTGS2 (0.47) | MAPTLMNAKDM4ERAB9AGAA | |
| SCHEMBL4279296 | 0.80 | MAPT (0.57) | MAPTLMNAKDM4EGAAAR | |
| SCHEMBL11851821 | 0.80 | CA12 (0.47) | MAPTLMNAKDM4EGAAAR | |
| SCHEMBL8805132 | 0.80 | SLC6A3 (0.50) | MAPTLMNAKDM4EGAAALDH1A1 | |
| SCHEMBL11845170 | 0.80 | HRH2 (0.49) | MAPTLMNAKDM4ERAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |