Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27537598 | 0.95 | CA12 (0.48) | MAPTALDH1A1TDP1LMNACA12 | |
| SCHEMBL11847293 | 0.88 | MEN1 (0.43) | MAPTALDH1A1TDP1LMNATARBP2 | |
| SCHEMBL11850461 | 0.87 | PTGS2 (0.47) | MAPTALDH1A1LMNATARBP2SMN1; SMN2 | |
| SCHEMBL11851821 | 0.87 | CA12 (0.47) | MAPTALDH1A1TDP1LMNACA12 | |
| SCHEMBL11840175 | 0.85 | MAPT (0.43) | MAPTALDH1A1TDP1LMNAFFAR1 | |
| SCHEMBL11848073 | 0.85 | LMNA (0.38) | MAPTALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL11834068 | 0.85 | LMNA (0.49) | MAPTALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL11842204 | 0.85 | HTT (0.46) | MAPTALDH1A1TDP1LMNATARBP2 | |
| SCHEMBL11841432 | 0.85 | LMNA (0.38) | MAPTALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL11837938 | 0.84 | POLB (0.47) | MAPTALDH1A1TDP1LMNATARBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |