Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | HSD17B4 | P51659 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11843347 | 0.86 | USP2 (0.44) | USP2KDM4EMAPTTSHRMEN1 | |
| SCHEMBL11855638 | 0.84 | KMT2A (0.40) | IRAK4USP2KDM4EMAPTTSHR | |
| SCHEMBL11845227 | 0.83 | HTR2A (0.39) | USP2KDM4EMAPTTSHRCYP1A2 | |
| SCHEMBL11850300 | 0.82 | ALDH1A1 (0.42) | USP2KDM4EMAPTTSHRCYP1A2 | |
| SCHEMBL11837989 | 0.80 | HSD17B1 (0.38) | USP2KDM4EMAPTTSHRCYP1A2 | |
| SCHEMBL11852623 | 0.79 | CHRM2 (0.41) | USP2KDM4EMAPTTSHRCYP1A2 | |
| SCHEMBL11854443 | 0.78 | KDM4E (0.34) | USP2KDM4EMAPTTSHRLTA4H | |
| SCHEMBL11842265 | 0.77 | DRD1 (0.48) | USP2KDM4EMAPTTSHRCYP2D6 | |
| SCHEMBL11851331 | 0.76 | HTR2A (0.39) | IRAK4PARP1MEN1KMT2AHTR2A | |
| SCHEMBL11841936 | 0.73 | TSHR (0.42) | USP2KDM4EMAPTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980788-A | XANTHENYL COMPOUNDS | SMITHKLINE CORPORATION (US) | 1976-09-14 | — | — | US | disclosed |