Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11844515 | 1.00 | MEN1 (0.41) | MEN1KMT2AATMPTPN1NISCH | |
| SCHEMBL6157468 | 0.73 | MEN1 (0.45) | MEN1KMT2AATMPTPN1MAOA | |
| SCHEMBL6159010 | 0.73 | MEN1 (0.45) | MEN1KMT2AATMPTPN1MAOA | |
| SCHEMBL29868676 | 0.72 | KDM4E (0.51) | MEN1KMT2AATMPTPN1MAOA | |
| SCHEMBL7759078 | 0.72 | KDM4E (0.51) | MEN1KMT2AATMPTPN1MAOA | |
| SCHEMBL7561038 | 0.71 | NISCH (0.54) | NISCHADRA2CADRA2BADRA2A | |
| SCHEMBL4764699 | 0.71 | MEN1 (0.51) | MEN1KMT2AATMPTPN1MAOA | |
| SCHEMBL27996594 | 0.71 | MEN1 (0.51) | MEN1KMT2AATMPTPN1MAOA | |
| SCHEMBL2364518 | 0.69 | GABRA1 (0.54) | MEN1KMT2AATMPTPN1ADRA1A | |
| SCHEMBL11870789 | 0.67 | NISCH (0.51) | NISCHADRA2CADRA2BADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935218-A | Imidazolinyl phenyl carbonyl compounds acid addition salts and related compounds | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |