Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841272 | 0.97 | ADRB2 (0.49) | ADRB2MEN1KMT2AALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL11841269 | 0.96 | ADRB2 (0.48) | ADRB2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7147265 | 0.93 | ADRB2 (0.58) | ADRB2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7147263 | 0.93 | ADRB2 (0.58) | ADRB2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL11848510 | 0.86 | MEN1 (0.52) | ADRB2MEN1KMT2AALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL11848505 | 0.85 | MEN1 (0.53) | ADRB2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL11849024 | 0.83 | SIGMAR1 (0.48) | ADRB2KMT2AALDH1A1SMN1; SMN2ADRB3 | |
| Hydrochloric Acid SCHEMBL11849017 | 0.82 | SIGMAR1 (0.50) | ADRB2KMT2AALDH1A1SMN1; SMN2ADRB3 | |
| SCHEMBL11847610 | 0.82 | ADRB2 (0.54) | ADRB2MAPK1NPSR1ADRB3ADRB1 | |
| SCHEMBL7150543 | 0.81 | ADRB1 (0.65) | ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976695-A | Halogen substituted α-(aminoalkyl)-3,4-dihydroxybenzyl alcohols | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |