Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 6/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846058 | 0.81 | EGFR (0.34) | EGFRERBB2LMNASMN1; SMN2KDM4E | |
| SCHEMBL9232636 | 0.79 | CA1 (0.70) | CA2CA9CA1CA12EGFR | |
| SCHEMBL11840357 | 0.76 | CYP2C19 (0.38) | CA2CA9CA1LMNASMN1; SMN2 | |
| SCHEMBL11860800 | 0.76 | CA1 (0.53) | CA2CA9CA1CA12EGFR | |
| SCHEMBL11844288 | 0.73 | CA2 (0.52) | CA2CA9CA1CA12EGFR | |
| SCHEMBL11873312 | 0.71 | CA1 (0.47) | CA2CA9CA1CA12EGFR | |
| SCHEMBL11873317 | 0.71 | CA1 (0.47) | CA2CA9CA1CA12EGFR | |
| SCHEMBL11720483 | 0.71 | CA12 (0.43) | CA2CA9CA1CA12EGFR | |
| SCHEMBL9236173 | 0.70 | SMN1; SMN2 (0.50) | CA2CA9CA1CA12EGFR | |
| SCHEMBL11843061 | 0.69 | GFER (0.35) | LMNASMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989690-A | ANTI-PARASITIC AGENTS ACTIVE AGAINST TRYPANOSOMIDAE | LILLY INDUSTRIES, LTD. (EN) | 1976-11-02 | — | — | US | disclosed |