Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11845655 | 0.87 | LMNA (0.44) | CYP2C19ALDH1A1LMNAGAAMAPK1 | |
| SCHEMBL11843061 | 0.81 | GFER (0.35) | ALDH1A1LMNARAB9ANPC1GAA | |
| SCHEMBL11843047 | 0.81 | LMNA (0.46) | CYP2C19ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL11838298 | 0.78 | MAPT (0.38) | CYP2C19ALDH1A1LMNAGAAMAPK1 | |
| SCHEMBL11835625 | 0.78 | LMNA (0.40) | CYP2C19ALDH1A1LMNARAB9AGAA | |
| SCHEMBL11835173 | 0.77 | RAB9A (0.41) | CYP2C19ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL11846064 | 0.76 | CA2 (0.44) | LMNAKDM4ESMN1; SMN2MAPTCA1 | |
| SCHEMBL11846058 | 0.73 | EGFR (0.34) | ALDH1A1LMNARAB9ANPC1GAA | |
| SCHEMBL11844761 | 0.72 | RXFP1 (0.36) | CYP2C19ALDH1A1LMNARAB9AGAA | |
| SCHEMBL11844768 | 0.71 | RXFP1 (0.35) | CYP2C19RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989690-A | ANTI-PARASITIC AGENTS ACTIVE AGAINST TRYPANOSOMIDAE | LILLY INDUSTRIES, LTD. (EN) | 1976-11-02 | — | — | US | disclosed |