Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11851033 | 0.89 | TSHR (0.49) | TSHRSMARCA2OPRK1LMNAGAA | |
| SCHEMBL11850497 | 0.81 | LMNA (0.45) | TSHRSMARCA2HDAC4HDAC8OPRK1 | |
| SCHEMBL11842418 | 0.80 | LMNA (0.44) | TSHRSMARCA2HDAC4HDAC8OPRK1 | |
| SCHEMBL11477847 | 0.80 | TSHR (0.56) | TSHRLMNAGAAADRA1AGABRA1 | |
| SCHEMBL11846111 | 0.75 | TSHR (0.68) | TSHRLMNAGAATP53 | |
| SCHEMBL11846615 | 0.75 | MEN1 (0.44) | TSHRGAA | |
| SCHEMBL11855311 | 0.75 | TSHR (0.58) | TSHRSMARCA2OPRK1LMNANR1I2 | |
| SCHEMBL11847604 | 0.74 | TSHR (0.65) | TSHRGAAKCNH2TP53 | |
| SCHEMBL9537414 | 0.71 | TSHR (0.46) | TSHRSMARCA2CYP11B2HDAC4HDAC8 | |
| SCHEMBL11746801 | 0.70 | TSHR (0.49) | TSHRSMARCA2LMNAGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969506-A | BRONCHODILATOR | SANDOZ, INC. (US) | 1976-07-13 | — | — | US | disclosed |