Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556526 | 0.82 | ALDH1A1 (0.53) | ALDH1A1TSHRFDPSTDP1HPGD | |
| SCHEMBL17345395 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRFDPSTDP1HPGD | |
| SCHEMBL6291111 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRFDPSTDP1HPGD | |
| SCHEMBL25192245 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRFDPSTDP1HPGD | |
| SCHEMBL919081 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRFDPSTDP1HPGD | |
| SCHEMBL27879203 | 0.78 | IGF1R (0.38) | ALDH1A1TSHRFDPSTDP1HPGD | |
| SCHEMBL25173455 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TSHRFDPSTDP1HPGD | |
| SCHEMBL13486796 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRFDPSTDP1HPGD | |
| SCHEMBL7196531 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TSHRFDPSTDP1HPGD | |
| SCHEMBL29101754 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TSHRFDPSTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931181-A | BACTERICIDE | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |