Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196531 | 0.89 | ALDH1A1 (0.47) | ALDH1A1TSHRFDPSTDP1TRIM24 | |
| SCHEMBL27002149 | 0.87 | ALOX5 (0.47) | ALDH1A1TSHRFDPSTDP1TRIM24 | |
| SCHEMBL7190150 | 0.86 | ALOX5 (0.50) | ALDH1A1TSHRFDPSTDP1TRIM24 | |
| SCHEMBL6556526 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRFDPSTDP1TRIM24 | |
| SCHEMBL918198 | 0.81 | TRPA1 (0.46) | ALDH1A1TSHRPDE3BPDE3AHMGCR | |
| SCHEMBL150381 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRFDPSTDP1TRIM24 | |
| SCHEMBL6931161 | 0.79 | PDE3B (0.41) | ALDH1A1TSHRTDP1PDE3BPDE3A | |
| SCHEMBL17853905 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRFDPSTDP1TRIM24 | |
| SCHEMBL7280410 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRFDPSTDP1TRIM24 | |
| SCHEMBL146097 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRFDPSTDP1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105884581-A | Method for preparing 2-(1-methylethyl)-5-[(E)-2-phenylethenyl]benzene-1,3-diol | 上海复星医药产业发展有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-104003848-B | (E)-3,5-dihydroxyl-4-isopropyl toluylene preparation methods | WUHAN NUOAN PHARMACY CO., LTD. (CN) | 2016-02-10 | — | — | CN | claimed |
| CN-103992212-B | Synthesis method for cis-benvitimod, and applications of cis-benvitimod | UNIV HEBEI SCIENCE & TECH | 2015-07-01 | — | — | CN | claimed |
| US-20230285327-A1 | DESOXYSCALINE DERIVATIVES WITH MODIFIED MESCALINE-LIKE ACTION | Mind Medicine, Inc. (US) | 2023-09-14 | — | — | US | disclosed |
| WO-2023091437-A1 | DESOXYSCALINE DERIVATIVES WITH MODIFIED MESCALINE-LIKE ACTION | Mind Medicine, Inc. (US) | 2023-05-25 | — | — | WO | disclosed |
| US-20230150906-A1 | DESOXYSCALINE DERIVATIVES WITH MODIFIED MESCALINE-LIKE ACTION | Mind Medicine, Inc. (US) | 2023-05-18 | — | — | US | disclosed |
| CN-105884581-A | Method for preparing 2-(1-methylethyl)-5-[(E)-2-phenylethenyl]benzene-1,3-diol | 上海复星医药产业发展有限公司 | 2016-08-24 | — | — | CN | disclosed |
| WO-2016100542-A1 | INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ADT PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |
| CN-103467281-B | A kind of phenol derivatives and application thereof | WUHAN INNERSE PHARMACEUTICALS CO., LTD. (CN) | 2016-03-23 | — | — | CN | disclosed |
| CN-104003848-B | (E)-3,5-dihydroxyl-4-isopropyl toluylene preparation methods | WUHAN NUOAN PHARMACY CO., LTD. (CN) | 2016-02-10 | — | — | CN | disclosed |
| CN-103992212-B | Synthesis method for cis-benvitimod, and applications of cis-benvitimod | UNIV HEBEI SCIENCE & TECH | 2015-07-01 | — | — | CN | disclosed |
| US-7868047-B2 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | WELICHEM BIOTECH INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| US-20100094041-A1 | ANTI-INFLAMMATORY AND PSORIASIS TREATMENT AND PROTEIN KINASE INHIBITION BY HYDROXY STILBENES AND NOVEL STILBENE DERIVATIVES AND ANALOGUES | WELICHEM BIOTECH INC. (CA) | 2010-04-15 | — | — | US | disclosed |
| US-20080139666-A1 | Anti-Inflammatory and Psoriasis Treatment and Protein Kinase Inhibition by Hydroxy Stilbenes and Novel Stilbene Derivatives and Analogues | WELICHEM BIOTECH INC. (CA) | 2008-06-12 | — | — | US | disclosed |
| EP-1554236-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | Welichem Biotech Inc. (CA) | 2005-07-20 | — | — | EP | disclosed |
| US-20050059733-A1 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | WELICHEM BIOTECH, INC. | 2005-03-17 | — | — | US | disclosed |
| WO-2004031117-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | WELICHEM BIOTECH INC. (CA) | 2004-04-15 | — | — | WO | disclosed |
| EP-1368306-A1 | NOVEL 1,2-DIPHENYLETHENE DERIVATIVES FOR TREATMENT OF IMMUNE DISEASES | Welichem Biotech Inc. (CA) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002057219-A1 | NOVEL 1,2-DIPHENYLETHENE DERIVATIVES FOR TREATMENT OF IMMUNE DISEASES | WELICHEM BIOTECH INC. (CA) | 2002-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059733-A1 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | NFKBIA, IKBKB, IKBKE | ALDH1A1 3063/4885TSHR 3934/4885FDPS 1586/4885 |
| US-20080139666-A1 | Anti-Inflammatory and Psoriasis Treatment and Protein Kinase Inhibition by Hydroxy Stilbenes and Novel Stilbene Derivatives and Analogues | LTK, MMP8, CHUK | ALDH1A1 4482/4885TSHR 2854/4885FDPS 2260/4885 |
| US-20100094041-A1 | ANTI-INFLAMMATORY AND PSORIASIS TREATMENT AND PROTEIN KINASE INHIBITION BY HYDROXY STILBENES AND NOVEL STILBENE DERIVATIVES AND ANALOGUES | CHUK, MAP3K8, MAP3K1 | ALDH1A1 4139/4885TSHR 4202/4885FDPS 2525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.