Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.52 |
| ▸ | ABAT | P80404 | 1/20 | 0.52 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.52 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13643409 | 0.89 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1TRIM24HPGD | |
| SCHEMBL150381 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1TRIM24HPGD | |
| SCHEMBL6556526 | 0.82 | ALDH1A1 (0.53) | ALDH1A1TSHRTDP1TRIM24HPGD | |
| SCHEMBL11849166 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1TRIM24HPGD | |
| SCHEMBL17345395 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1TRIM24HPGD | |
| Alcohol SCHEMBL28096074 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHRTDP1TRIM24HPGD | |
| Syringaldehyde SCHEMBL28294707 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1TRIM24HPGD | |
| SCHEMBL919081 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1TRIM24HPGD | |
| SCHEMBL14302478 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1TRIM24HPGD | |
| SCHEMBL8155224 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1TRIM24HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872711-B2 | β-substituted β-aminoethyl phosphonate derivatives | ILEX ONCOLOGY RESEARCH S.A. (CH) | 2005-03-29 | — | — | US | disclosed |
| EP-1330463-A2 | BETA-SUBSTITUTED BETA-AMINOETHYL PHOSPHONATES | Ilex Oncology Research S.A. (CH) | 2003-07-30 | — | — | EP | disclosed |
| US-20020111488-A1 | Beta-substitued beta-aminoethyl phosphonate derivatives | ILEX PRODUCTS, INC. | 2002-08-15 | — | — | US | disclosed |
| WO-2002034756-A2 | BETA-SUBSTITUTED BETA-AMINOETHYL PHOSPHONATES | ILEX ONCOLOGY RESEARCH S.A. (CH) | 2002-05-02 | — | — | WO | disclosed |
| US-3931181-A | BACTERICIDE | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111488-A1 | Beta-substitued beta-aminoethyl phosphonate derivatives | APOB, PHOSPHO1, APOL1 | ALDH1A1 3772/4885TSHR 4263/4885TDP1 2151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.