SCHEMBL11851998

SCHEMBL11851998

CCCC(=O)SCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.50
HDAC3 O15379 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HSD17B10 Q99714 2/20 0.45
GMNN O75496 1/20 0.45
TP53 P04637 1/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
THRB P10828 1/20 0.45
CYP2C9 P11712 1/20 0.45
BLM P54132 1/20 0.45
AKR1B1 P15121 1/20 0.44
ALDH1A1 P00352 3/20 0.43
CYP2D6 P10635 2/20 0.43
GPR84 Q9NQS5 7/20 0.42
PPARG P37231 7/20 0.42
PPARD Q03181 7/20 0.42
PPARA Q07869 7/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574534 0.84 GPR84 (0.60) HSD17B10GMNNTP53POLBMAPT
SCHEMBL11440512 0.78 FFAR3 (0.55) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL9564065 0.76 ALDH1A1 (0.50) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL474039 0.76
SCHEMBL6890970 0.75 TSHR (0.46) HDAC3HDAC1HDAC2HDAC8HSD17B10
SCHEMBL3869646 0.74
SCHEMBL2254887 0.72
SCHEMBL3874809 0.72 NOS3 (0.46) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL21538114 0.72
SCHEMBL25261761 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3986930-A COLORIMETRY, S-ACYL COMPOUNDS DAINIPPON PHARMACEUTICAL CO., LTD. (JA) 1976-10-19 US disclosed