Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832945 | 0.91 | CYP19A1 (0.44) | PPARAIDO1TDO2 | |
| SCHEMBL11848999 | 0.90 | PPARA (0.43) | PPARAMEN1KMT2A | |
| SCHEMBL11851774 | 0.90 | LMNA (0.42) | LMNATP53HTT | |
| SCHEMBL11856958 | 0.84 | ATM (0.45) | PPARAIDO1TDO2GRIN2BLMNA | |
| SCHEMBL11853610 | 0.84 | HCRTR2 (0.43) | PPARAIDO1LMNATP53HTT | |
| SCHEMBL11857854 | 0.84 | TRPA1 (0.42) | PPARAIDO1GRIN2BLMNATP53 | |
| SCHEMBL11854875 | 0.83 | PPARG (0.40) | PPARAIDO1TDO2LMNATP53 | |
| SCHEMBL8395600 | 0.82 | TP53 (0.50) | LMNATP53HTTHSD17B10 | |
| SCHEMBL11855888 | 0.81 | IDO1 (0.45) | IDO1HTTMEN1KMT2A | |
| SCHEMBL11855715 | 0.81 | LMNA (0.40) | IDO1LMNATP53HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991201-A | 1-(β-Aryl-β-R-ethyl)imidazoles as antimicrobial agents | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-09 | — | — | US | disclosed |