Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 4/20 | 0.56 |
| ▸ | PLG | P00747 | 2/20 | 0.56 |
| ▸ | KLK1 | P06870 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11852908 | 1.00 | PLAU (0.56) | PLAUPLGKLK1F2KLKB1 | |
| SCHEMBL11854060 | 0.93 | RECQL (0.60) | PLAUPLGKLK1F2KLKB1 | |
| SCHEMBL24704151 | 0.81 | PDE4A (0.51) | PLAUPLGKLK1F2KLKB1 | |
| SCHEMBL10399101 | 0.79 | CES2 (0.46) | PLAUPLGKLK1F2KLKB1 | |
| SCHEMBL10399120 | 0.79 | CES2 (0.46) | PLAUPLGKLK1F2KLKB1 | |
| SCHEMBL29041273 | 0.79 | CES2 (0.46) | PLAUPLGKLK1F2KLKB1 | |
| SCHEMBL28519063 | 0.79 | CES2 (0.46) | PLAUPLGKLK1F2KLKB1 | |
| SCHEMBL29483453 | 0.79 | CES2 (0.46) | PLAUPLGKLK1F2KLKB1 | |
| SCHEMBL11844414 | 0.78 | RECQL (0.79) | PLAURECQLALDH1A1MAPTHPGD | |
| SCHEMBL28990052 | 0.78 | RECQL (0.79) | PLAURECQLALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3970622-A | Heat stabilizers for polyvinyl chloride (β-amino-β-arylacrylonitriles) | AMERICAN CYANAMID COMPANY (US) | 1976-07-20 | — | — | US | disclosed |
| US-3970644-A | Heat stabilizers for polyvinyl chloride (β-amino-β-arylacrylamides) | AMERICAN CYANAMID COMPANY (US) | 1976-07-20 | — | — | US | disclosed |