Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 15/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24704150 | 0.95 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DCES2 | |
| SCHEMBL4824892 | 0.85 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4824887 | 0.85 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10773877 | 0.83 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL10773871 | 0.83 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL10399101 | 0.81 | CES2 (0.46) | PDE4APDE4BPDE4CPDE4DCES2 | |
| SCHEMBL11852913 | 0.81 | PLAU (0.56) | PDE4APDE4BPDE4CPDE4DCES2 | |
| SCHEMBL28519063 | 0.81 | CES2 (0.46) | PDE4APDE4BPDE4CPDE4DCES2 | |
| SCHEMBL10399120 | 0.81 | CES2 (0.46) | PDE4APDE4BPDE4CPDE4DCES2 | |
| SCHEMBL11852908 | 0.81 | PLAU (0.56) | PDE4APDE4BPDE4CPDE4DCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255228-A1 | COMPOSITION, CURED PRODUCT OR COMPACT, OPTICAL MEMBER, AND LENS | 富士フイルム株式会社 | 2022-12-08 | — | — | WO | disclosed |